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AWWA ACE70543

AWWA ACE70543 The Problem of Endpoint: Should We Be Concerned about Perchlorate or Thyroid Effects?

Conference Proceeding by American Water Works Association, 11/01/2009

Bull, Richard J.

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This powerpoint presentation begins by providing a brief overview of the cumulative risk of health effects of perchlorate, which became more apparent with the proposedperchlorate rule. Topics covered include:development of the PHG for perchlorate;basis for differences between rats and humans;chemicals that affect the thyroid;chemicals in drinking water that can affect thyroid;adaptive nature of thyroid function;rat vs. human; ClOsub4/subsup-/sup vs. other drinking water chemicals; and,indication of need for cumulative risk for NIS inhibitors. Includes tables, figures.

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